Photoinduced efficient synthesis of cyanoalkylsulfonylated oxindoles via sulfur dioxide insertion
Fan Teng1, Juan Du1,2, Changping Xun1
1College of Chemistry and Materials Science, Hunan Agricultural University, Changsha 410128, China. gqw1216@hunau.edu.cn.
Abstract:
A visible-light-promoted radical cascade reaction of N-arylacrylamide and cyclobutanone oxime esters with sulfur dioxide insertion is established. Mainly through the exploration of the visible light wavelength, it is found that the light source has a certain influence on the formation of cyanoalkylsulfonylated oxindoles, furnishing a range of sulfones in good to excellent yields. This protocol presents good functional group compatibility and does not require transition metals, photosensitizers, external bases, or oxidants.
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