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Updated: Oct 17, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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New Methods for the Synthesis of Spirocyclic Cephalosporin Analogues

Alan X Zhao1, Louise E Horsfall2, Alison N Hulme1

  • 1EaStChem School of Chemistry, The University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, UK.

Molecules (Basel, Switzerland)
|October 13, 2021
PubMed

Keywords:
Michael-type reactionspiro-cephalosporinspiro-cyclisation

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