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Updated: Oct 17, 2025

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
Published on: January 25, 2016
Atrial Fibrillation Is Not Associated With Sudden Sensorineural Hearing Loss
Trong-Zong Chen1,2, Bi-Hua Cheng3,4, Hsiao-Yun Hu5,6,7
1Department of Gastroenterology and Hepatology, Taipei City Hospital, Taipei.
Insights
This study investigated the link between atrial fibrillation (AF) and sudden sensorineural hearing loss (SSNHL). Researchers found no significant association between AF and the risk of developing SSNHL.
Area of Science:
- Cardiology
- Otolaryngology
- Epidemiology
Background:
- Atrial fibrillation (AF) is a common cardiac arrhythmia.
- Sudden sensorineural hearing loss (SSNHL) is an idiopathic condition requiring prompt diagnosis and treatment.
- Understanding potential risk factors for SSNHL is crucial for early intervention.
Purpose of the Study:
- To investigate the potential association between atrial fibrillation (AF) and the incidence of sudden sensorineural hearing loss (SSNHL).
- To identify risk factors associated with SSNHL in a large cohort.
- To evaluate the role of antiplatelet and anticoagulation medications in SSNHL.
Main Methods:
- A population-based retrospective cohort study using Taiwan's National Health Insurance database (2000-2011).
- 14,698 patients with AF were propensity score-matched 1:1 with non-AF controls.
- Multiple logistic regression analyses were employed to assess the risk of SSNHL.
Main Results:
- No statistically significant association was found between atrial fibrillation and the risk of sudden sensorineural hearing loss (OR: 0.89, 95% CI: 0.64-1.23, P = .467).
- Male gender, age (45-74 years), hyperlipidemia, and hypertension were identified as risk factors for SSNHL.
- Aspirin use was associated with a reduced rate of SSNHL (OR: 0.67, 95% CI: 0.49-0.94, P = .019).
Conclusions:
- Atrial fibrillation is not a significant risk factor for sudden sensorineural hearing loss.
- Male gender, older age, hyperlipidemia, and hypertension are associated with an increased risk of SSNHL.
- Aspirin may have a protective effect against SSNHL.
Objectives:
The aim of this study is to assess the association between atrial fibrillation (AF) and sudden sensorineural hearing loss (SSNHL).
Methods:
This study was conducted by searching the longitudinal health insurance database of the Taiwan National Health Insurance Program for relevant information from January 1, 2000, to December 31, 2011. Patients with AF were matched with non-AF controls with a 1:1 strategy according to propensity scores. Multiple logistic regression analyses were performed to determine the risk of SSNHL.
Results:
In total, 14 698 patients with AF were matched with the same number of non-AF patients as controls. After propensity score matching, the use of antiplatelet or anticoagulation medications and the occurrence of SSNHL were found to have a significant difference between AF and non-AF patients. The occurrence of SSNHL was found to be higher in men, those of 45 to 74 years old, and patients with hypertension in both AF and non-AF groups. Multiple logistic regression analyses revealed that male gender, age between 45 and 74 years, hyperlipidemia, and hypertension are risk factors for SSNHL. The use of aspirin was found to reduce the rate of SSNHL (odds ratio [OR]: 0.67, 95% CI: 0.49-0.94, P = .019), but AF was not found to be a risk factor for SSNHL (OR: 0.89, 95% CI: 0.64-1.23, P = .467).
Conclusion:
The association between AF and SSNHL is not significant.
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