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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
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Case of fatal eastern equine encephalitis.
Evan P Dexter1, Donn D Dexter2, Christopher W Lindsay3
1University of Wisconsin, Eau Claire, USA.
Idcases
|October 14, 2021
Summary
Eastern Equine Encephalitis (EEE) is a severe arbovirus transmitted by mosquitoes, often fatal in symptomatic patients. This case report details classic symptoms, MRI findings, and autopsy results, highlighting the virus
Area of Science:
- Neurology
- Infectious Diseases
- Public Health
Background:
- Eastern Equine Encephalitis (EEE) is a rare but severe arbovirus transmitted by infected mosquitoes.
- EEE infection in humans typically leads to critical illness with a high fatality rate.
Observation:
- This report details a fatal case of EEE presenting with classic clinical symptoms and diagnostic findings.
- High-quality MRI images illustrate characteristic radiographic findings of EEE infection.
- Autopsy findings include gross and microscopic examination of brain tissue pathology.
Findings:
- Confirmatory laboratory results supported the diagnosis of EEE.
- Pathologic specimens provided definitive evidence of EEE-induced brain tissue damage.
Implications:
- The findings underscore the severity and diagnostic features of EEE.
- Potential climate change and habitat encroachment may be driving a westward expansion of EEE in the United States.
- This case highlights the importance of recognizing EEE in endemic and expanding regions.
