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Retinal Scan with Optical Coherence Tomography in Adult Attention Deficit Hyperactivity Disorder
Turk Psikiyatri Dergisi = Turkish Journal of Psychiatry
|October 14, 2021
Summary
Adults with attention deficit hyperactivity disorder (ADHD) show reduced retinal nerve fiber layer (RNFL) thickness. This finding suggests RNFL measurements may serve as biomarkers for monitoring ADHD progression.
Area of Science:
- Ophthalmology
- Neuroscience
- Psychiatry
Background:
- Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder impacting adults.
- Ocular microstructural changes in adult ADHD are not well-established.
Purpose of the Study:
- To compare retinal nerve fiber layer (RNFL) thicknesses in adult ADHD cases versus healthy controls.
- To investigate potential ocular biomarkers for ADHD.
Main Methods:
- Employed Spectral Domain Optical Coherence Tomography (OCT) for precise retinal imaging.
- Included 26 adult ADHD patients (52 eyes) and 26 age/gender-matched healthy controls (52 eyes).
Main Results:
- Adult ADHD participants exhibited significantly lower RNFL thickness.
- Reduced central macular thickness (CMT), ganglion cell complex (GCC), and macular ring averages (MIRAVG, MOR-AVG) were observed in the ADHD group.
Conclusions:
- This is the first study to report reduced RNFL thickness in adult ADHD.
- RNFL thickness may be a potential biomarker for monitoring ADHD progression due to its quantitative nature.

