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Design, synthesis, and initial immunological evaluation of glycoconjugates based on saponin adjuvants and the Tn

Roberto Fuentes1, Leire Aguinagalde1, Nagore Sacristán1

  • 1Chemical Immunology Laboratory, CIC bioGUNE, Basque Research and Technology Alliance (BRTA), 48160 Derio, Spain. afernandeztejada@cicbiogune.es.

Chemical Communications (Cambridge, England)
|October 14, 2021
PubMed

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Conjugated Proteins

Simple proteins and protein complexes contain only amino acids. In contrast, many other proteins, called conjugated proteins, covalently bond with non-protein moieties.
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
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