Laser-Induced Graphene-Functionalized Field-Effect Transistor-Based Biosensing: A Potent Candidate for COVID-19...

Area of Science:

• Nanotechnology
• Biosensing
• Materials Science

Background:

• Effective control of the COVID-19 pandemic necessitates rapid and accurate diagnostic tests.
• Nanobiosensors, particularly those utilizing graphene, present a viable approach for sensitive biomarker detection.
• Graphene field-effect transistors (FETs) offer high precision in detecting analytes, even in complex biological samples.

Purpose of the Study:

• To review recent advancements in graphene-FET biosensing platforms for disease detection, with a focus on COVID-19.
• To analyze common graphene fabrication and transfer methods for biosensing applications.
• To highlight the advantages of laser-induced graphene (LIG) as a novel synthesis technique.

Main Methods:

• Literature review of graphene-FET biosensor platforms for disease detection.
• Analysis of graphene manufacturing techniques, including laser-induced graphene (LIG).
• Discussion of the advantages and disadvantages of various graphene fabrication methods.

Main Results:

• Graphene integration significantly enhances biosensor performance.
• Graphene-FETs demonstrate precise detection capabilities for biomarkers.
• Laser-induced graphene (LIG) emerges as a promising fabrication method with distinct benefits.

Conclusions:

• Graphene-FET biosensors are highly promising for rapid and sensitive COVID-19 detection.
• Fabrication and transfer methods are critical considerations for developing effective graphene biosensors.
• Further research into advanced fabrication techniques like LIG is warranted.