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Comparative analysis of COVID-19 case fatality rate between two waves in Nepal
Sulochan Gc1, Ashok Khanal1, Atmika Paudel2
1Institute of Medicine, Maharajgunj Medical Campus, Tribhuvan University, Kathmandu, Nepal.
Influenza and Other Respiratory Viruses
|October 15, 2021
Summary
Nepal
Area of Science:
- Epidemiology
- Public Health
- Infectious Diseases
Background:
- The first COVID-19 case in Nepal was reported in January 2020.
- October 2020 saw a significant surge in cases.
- A subsequent peak in May 2021 exhibited a substantial rise in daily cases and deaths.
Purpose of the Study:
- To analyze the COVID-19 case fatality rates (CFR) in Nepal.
- To compare CFR between the October 2020 and May 2021 peaks.
- To investigate demographic factors associated with increased mortality.
Main Methods:
- Comparative analysis of COVID-19 case and death data.
- Examination of case fatality rates during two distinct epidemic peaks.
- Stratification of mortality by age and comorbidity status.
Main Results:
- The May 2021 peak showed a 2-fold increase in daily cases and a 10-fold increase in daily deaths compared to October 2020.
- An elevated death rate was observed among younger adults.
- Increased mortality was also noted in individuals without pre-existing comorbidities.
Conclusions:
- The study highlights a concerning rise in COVID-19 case fatality rates in Nepal between the 2020 and 2021 peaks.
- Younger adults and those without comorbidities were disproportionately affected, suggesting a shift in vulnerable populations.
- These findings underscore the need for targeted public health interventions and further research into the factors driving these trends.
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