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[Prevalence estimation of Autism Spectrum disorders in chilean urban population]
Carolina Yáñez1, Paulina Maira2, Constanza Elgueta2
1Hospital Clínico San Borja Arriarán, Santiago, Chile.
Insights
This study estimated Autism Spectrum Disorder (ASD) prevalence in Santiago, Chile, finding a rate of 1.95%. Early multidisciplinary intervention is crucial for affected children.
Area of Science:
- Pediatric Epidemiology
- Neurodevelopmental Disorders
Background:
- Global Autism Spectrum Disorder (ASD) prevalence ranges from 0.5-1%.
- Prevalence of ASD in Chile remained unestablished prior to this study.
Purpose of the Study:
- To determine the prevalence of ASD in two urban communes within Santiago, Chile.
- To provide initial data on ASD rates in the Chilean population.
Main Methods:
- A cross-sectional study involving 272 children aged 18-30 months.
- Screening with the Modified Checklist for Autism in Toddlers (M-CHAT), followed by clinical diagnosis by a pediatric neurologist.
- Diagnostic confirmation utilized the Autism Diagnostic Observation Schedule - Second Version (ADOS-2).
Main Results:
- A prevalence of 1.95% (95% CI 0.81-4.63) for ASD was identified.
- Out of 44 children with an altered M-CHAT, 5 received a clinical ASD diagnosis.
- The study observed a 4:1 male to female ratio in diagnosed cases.
Conclusions:
- This research presents the first ASD prevalence estimate for two communes in Santiago, Chile.
- The observed high prevalence underscores the necessity for resources supporting early, multidisciplinary care for children with ASD.
Introduction:
The prevalence of Autism Spectrum Disorder has increased, varying between 0.5 and 1% around the world. The prevalence of ASD in Chile is unknown.
Objective:
To estimate the prevalence of ASD in two urban communes of Santiago, Chile.
Subjects And Method:
Cross-sectional epidemiological study. 272 children aged between 18-30 months who attended well-child visits at two Family Health Centers in two urban communes of Santiago participated. Consecutive sampling was used and chil dren who were already being monitored by neurology were excluded. Screening was performed using the Modified Checklist for Autism in Toddlers (M-CHAT). Those children with altered M-CHAT were evaluated by a pediatric neurologist at the San Borja Arriarán Clinical Hospital and diagnosed with ASD according to clinical criteria. The Autism Diagnostic Observation Schedule - Second Ver sion (ADOS-2) was used as a diagnostic complement. The prevalence of ASD was estimated with a 95% confidence interval.
Results:
44 children had altered M-CHAT; 5 of them were clinically diagno sed with ASD. A 1.95% prevalence of ASD (95% CI 0.81-4.63) was obtained, with a sex distribution of 4 boys per 1 girl.
Conclusions:
This study is the first estimate of ASD prevalence in two communes of Santiago, Chile. A high prevalence of this condition was observed, which highlights the need for obtaining resources for an early multidisciplinary approach for these patients.
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