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Published on: February 9, 2011
[Serratia marcescens multifocal osteomyelitis in a child with chronic granulomatous disease]
María Eugenia Castro-Moraga1, Paulina Coria1, Natalia Conca1
1Facultad de Medicina, Universidad de Chile, Santiago, Chile.
Abstract:
Chronic granulomatous disease (CGD) is a rare primary immuno-deficiency. It is characterized by an alteration in the function of phagocytes causing recurrent bacterial and fungal infections. This is a case report of a child with multifocal osteomyelitis by Serratia marcescens, an infrequent as a cause of bone infections, although associated with CGD. The study of infections with clinical presentation and unusual agents should lead to suspicion of CGD. The diagnosis early in life, as well as timely antimicrobial treatment and the subsequent antimicrobial prophylaxis will avoid infectious recurrences and sequelae.
Insights
Chronic granulomatous disease (CGD) is a rare immune deficiency. Early diagnosis and treatment of unusual infections like Serratia marcescens osteomyelitis in children can prevent severe complications.
Area of Science:
- Immunology
- Pediatrics
- Infectious Diseases
Background:
- Chronic granulomatous disease (CGD) is a rare primary immunodeficiency affecting phagocyte function.
- CGD predisposes individuals to recurrent, severe bacterial and fungal infections.
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