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Prevalence of pseudophakia: U.S. population-based study.

Ellen A Erie1, David O Hodge, Michael A Mahr

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|October 15, 2021
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Summary

Pseudophakia prevalence in Olmsted County, Minnesota, surged 590% over 30 years, reaching 6.5% in 2018. Most older adults, especially those 85+, are pseudophakic, benefiting from cataract surgery.

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Area of Science:

  • Ophthalmology
  • Public Health
  • Epidemiology

Background:

  • Pseudophakia, the state of having an intraocular lens after cataract surgery, is increasingly common due to aging populations and advancements in surgical techniques.
  • Understanding the prevalence and trends of pseudophakia is crucial for healthcare planning and resource allocation.

Purpose of the Study:

  • To determine the current prevalence and temporal trends of pseudophakia in a well-defined U.S. population.
  • To calculate pseudophakia prevalence and associated mortality rates in Olmsted County, Minnesota, from 1988 to 2018.

Main Methods:

  • A population-based cohort study utilizing the Rochester Epidemiology Project (REP) databases.
  • Identification of pseudophakia cases in Olmsted County residents between 1988 and 2018.
  • Calculation of age- and sex-specific prevalence rates and assessment of trends using Poisson regression; mortality rates estimated via Kaplan-Meier analysis.

Main Results:

  • In 2018, 6.5% of Olmsted County residents (10,024 individuals) were pseudophakic.
  • Prevalence increased significantly over 30 years (590%) and 10 years (67%), with higher rates in women and older age groups (88% of those 85+).
  • Pseudophakia was associated with lower all-cause mortality compared to the general population.

Conclusions:

  • Pseudophakia is highly prevalent in older adults, with most individuals aged 75 and above being pseudophakic in at least one eye by 2018.
  • These findings highlight the significant impact of cataract surgery on the visual status and health outcomes of the aging population.