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Trans-resveratrol electrochemical detection using portable device based on unmodified screen-printed electrode
Rosecler Scacchetti Klein1, Maiara Mitiko Taniguchi2, Patricia Daniele Dos Santos3
1Laboratório de Materiais, Macromoleculas e Compósitos (LaMMAC), Universidade Tecnológica Federal do Paraná (UTFPR), Rua Marcílio Dias 635, 86812-460 Apucarana, State of Paraná, Brazil; Group of Polymeric Materials and Composites (GMPC), Department of Chemistry, State University of Maringá (UEM), 87020-900, Maringá, PR, Brazil.
A new method uses unmodified electrodes and differential pulse voltammetry (DPV) for trans-resveratrol (t-RESV) detection. This approach offers a portable and reproducible way to quantify this antioxidant in drugs and complex samples.
Area of Science:
- Electrochemistry
- Analytical Chemistry
- Biochemistry
Background:
- Trans-resveratrol (t-RESV) is a natural antioxidant with pharmaceutical potential.
- Existing electrochemical methods for t-RESV often use modified electrodes, which can be laborious and lack reproducibility.
Purpose of the Study:
- To develop a new, simpler, and more reproducible electrochemical method for t-RESV detection.
- To optimize and validate this method for quantifying t-RESV in commercial drugs and complex matrices.
Main Methods:
- Utilized unmodified screen-printed electrodes with differential pulse voltammetry (DPV).
- Employed response surface methodology to optimize DPV parameters (pulse time, potential, step).
- Validated the analytical method for limits of detection and quantification.
Main Results:
- Developed a predictive mathematical model for t-RESV quantification using DPV.
- Successfully quantified t-RESV in commercial drug samples.
- Demonstrated sensor selectivity for t-RESV in complex matrices.
- The system is portable and self-powered, facilitating point-of-care analysis.
Conclusions:
- The proposed method offers a robust, reproducible, and portable electrochemical approach for t-RESV determination.
- This technique simplifies analysis and enables point-of-care applications for this important antioxidant.
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