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Related Concept Videos

Aneurysm I: Introduction01:30

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An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
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Related Experiment Video

Updated: Oct 16, 2025

Ovine Lumbar Intervertebral Disc Degeneration Model Utilizing a Lateral Retroperitoneal Drill Bit Injury
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Could gas-filled pseudocyst mimick extruded disc herniation?

Murat Şakir Ekşi1, Emel Ece Özcan-Ekşi2, Ömer Orhun3

  • 1Acıbadem Mehmet Ali Aydınlar University, School of Medicine, Department of Neurosurgery, Istanbul, Turkey.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|October 17, 2021
PubMed
Summary

Gas-filled pseudocysts (GFP) are rare spinal conditions, mostly affecting men in their 60s. This systematic review highlights their presentation, diagnosis, and successful surgical management, with most patients achieving full recovery.

Keywords:
Disc degenerationDiscal cystGas-filled pseudocystModic changesRadiculopathy

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Area of Science:

  • Neurosurgery
  • Radiology
  • Spinal Pathology

Background:

  • Gas-filled pseudocysts (GFP) are infrequently reported, lacking comprehensive reviews on disease overview and management.
  • Existing literature consists primarily of case reports and small case series.

Purpose of the Study:

  • To conduct a systematic review of gas-filled pseudocyst cases.
  • To present an exemplary case and discuss pathogenesis theories.
  • To provide a comprehensive overview of GFP and its management.

Main Methods:

  • Systematic review adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
  • Literature search utilizing two major data search engines.
  • Inclusion of a novel case presentation and analysis.

Main Results:

  • A cohort of 53 articles was reviewed, alongside a presented case.
  • The average patient age was 59.47 years, with a male predominance (54.1%).
  • Common symptoms included radicular signs in lower limbs, often with low back pain (67%).
  • Diagnosis most frequently occurred in the lower lumbar spine (L4-L5 and L5-S1).
  • Surgery was the primary treatment (80%), leading to complete recovery in 79.1% of patients.

Conclusions:

  • Gas-filled pseudocysts are rare, typically affecting middle-aged to older men.
  • Accurate diagnosis via imaging is crucial for appropriate treatment.
  • Management should align with treatments for other spinal pathologies causing nerve root compression.