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Disability-adjusted life years for acute bronchiolitis in infants in Colombia

Jefferson Antonio Buendía1, Diana Guerrero Patiño2

  • 1Grupo de Investigación en Farmacología y Toxicología, Department of Pharmacology and Toxicology, School of Medicine, Department of Pharmacology and Toxicology, School of Medicine, University of Antioquia, Colombia.

The Pan African Medical Journal
|October 18, 2021
PubMed

Insights

Acute bronchiolitis significantly impacts Colombian infants, causing substantial years of life lost. This study quantifies the disease burden, highlighting the need for enhanced prevention strategies like vaccination.

Area of Science:

  • Pediatrics
  • Epidemiology
  • Public Health

Background:

  • Acute bronchiolitis is a primary cause of infant hospitalization globally.
  • The societal impact, measured in years of life lost, remains under-quantified.
  • This study addresses the knowledge gap by assessing the burden of acute bronchiolitis in Colombian infants.

Purpose of the Study:

  • To determine the Disability-Adjusted Life Years (DALYs) for acute bronchiolitis in infants in Colombia.
  • To quantify the years of life lost and years lived with disability due to this condition.

Main Methods:

  • Utilized data from Colombia's national epidemiological surveillance system.
  • Calculated DALYs by summing years of life lost and years lived with disability.
  • Employed a bootstrapped method with 10,000 iterations using the DALYs calculator package in R.

Main Results:

  • In 2019, acute bronchiolitis resulted in 447,434 years of life lost among Colombian infants.
  • The estimated rate was 34 DALYs per 1000 person-years.
  • A 95% confidence interval for DALYs was 30-39 per 1000 person-years.

Conclusions:

  • The study reveals a high disease burden associated with acute bronchiolitis in Colombia.
  • Highlights the need to promote prevention strategies, including vaccination, to mitigate morbidity.
  • Emphasizes the importance of addressing acute bronchiolitis to reduce its societal impact.
Abstract

Keywords:
BronchiolitisColombiaglobal burden of disease

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