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Updated: Oct 16, 2025

Functional Characterization of RING-Type E3 Ubiquitin Ligases In Vitro and In Planta
Published on: December 5, 2019
Nucleotide-binding leucine-rich repeat proteins: a missing link in controlling cell fate and plant adaptation to
Feifei Huang1,2, Feihua Wu3, Min Yu3
1College of Life and Oceanography Sciences, Shenzhen University, Shenzhen, Guangdong 518060, China.
Abstract:
Programmed cell death is a tightly regulated genetically controlled process that leads to cell suicide and eliminates cells that are either no longer needed or damaged/harmful. Nucleotide-binding leucine-rich repeat proteins have recently emerged as a novel class of Ca2+-permeable channels that operate in plant immune responses. This viewpoint argues that the unique structure of this channel, its permeability to other cations, and specificity of its operation make it an ideal candidate to mediate cell signaling and adaptive responses not only to pathogens but also to a broad range of abiotic stress factors.
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