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Updated: Oct 16, 2025
Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
Published on: March 12, 2015
Enhancement of the hydrophilic feruloyl glycerol synthesis using A-35 as a catalyst and its functional
Xinying Wang1, Xiaowei Chen1, Shangde Sun1
1Lipid Technology and Engineering, School of Food Science and Engineering, Henan University of Technology, Lianhua Road 100, Zhengzhou 450001, Henan Province, P. R. China. shangdesun@haut.edu.cn.
Abstract:
Feruloyl glycerol (FG) is the hydrophilic ester of ferulic acid (FA), which has a high solubility in water and a strong ability to resist ultraviolet (UV) radiation. In this work, several solid acids were used as novel economical catalysts and FA was used as a cheap substrate for FG preparation. The effects of reaction variables on the esterification of FA with glycerol were investigated and optimized by response surface methodology (RSM). Results showed that a cheap solid acid cation exchange resin A-35 showed the best performance for esterification. The reaction conditions were optimized by RSM as follows: 15 : 1 (glycerol/FA) substrate molar ratio and 14% catalyst loading at 90 °C for 7 h. The maximum FG yield (98.50 ± 0.58%) was achieved under the optimized conditions. The activation energy of the esterification was 53.71 kJ mol-1. The results of UV absorbance showed that FG had good anti-UV activity and photostability, which can be used as a potential antioxidant and UV absorber in food and sunscreen products.
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