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Two new dinor-eudesmane sesquiterpenoids from the roots of Chloranthus multistachys
Xiao-Yu Xie1, Yi-Xuan Yang1, Xin Gao1
1School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China.
Abstract:
Two new dinor-eudesmane sesquiterpenoids, named multistalin A (1), and multistalin B (2), together with three sesquiterpene glycosides (3-5), and a norlabdane-type diterpene (6) were isolated from the root extract of Chloranthus multistachys Pei. Their structures were elucidated on the basis of spectroscopic analysis including 1D, 2D NMR techniques and HR-ESI-MS. In addition, the cytotoxicity activities of the isolated compounds against selected cancer cells (Hela and A-549) were evaluated by MTT assay.
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