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T Cell Types and Functions

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...

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Related Experiment Video

Updated: Oct 16, 2025

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice

Published on: January 25, 2017

Interleukin-23 in perspective

Jonathan P Sherlock^1,2, Daniel J Cua¹

¹Janssen Research & Development, Spring House, PA, USA.

Rheumatology (Oxford, England)

|October 20, 2021

Summary

No abstract available in PubMed .

Keywords:

IL-23p19-specific inhibitors biologic biologic therapy cytokines interleukin-23 psoriasis psoriatic psoriatic arthritis psoriatic disease tumour necrosis factor inhibitors

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