Related Experiment Video

Updated: Oct 16, 2025

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System
03:49

Anogenital Distance and Perineal Measurements of the Pelvic Organ Prolapse POP Quantification System

Published on: September 20, 2018

19.7K

Maternal risk factors for paediatric inguinal hernia

Nathalie Auger1,2,3, Francesca Del Giorgio3, Annie Le-Nguyen4

  • 1University of Montreal Hospital Research Centre, Montreal, Quebec, Canada.

The British Journal of Surgery
|October 20, 2021
PubMed

Insights

Maternal history of inguinal hernia or connective tissue disorders increases a child's risk for developing paediatric inguinal hernias. This association varied between sexes, highlighting potential genetic or environmental factors.

Area of Science:

  • Pediatric Surgery
  • Genetics
  • Public Health

Background:

  • Paediatric inguinal hernia risk factors are not well understood.
  • This study investigates the link between maternal conditions and childhood hernia development.

Purpose of the Study:

  • To assess if maternal inguinal hernia or connective tissue disorders increase paediatric inguinal hernia risk.
  • To examine sex-specific associations in children up to 13 years of age.

Main Methods:

  • Longitudinal cohort study in Quebec, Canada (2006-2019).
  • Followed 786,322 children from birth to 13 years.
  • Used Cox proportional hazards regression to analyze associations.

Main Results:

  • Children with maternal inguinal hernia had 2.92 times higher risk.
  • Children with maternal connective tissue disorders had 1.30 times higher risk.
  • Maternal hernias strongly linked to girls' risk (HR 5.34); maternal connective tissue disorders linked to boys' risk (HR 1.35).

Conclusions:

  • Maternal inguinal hernias and connective tissue disorders are associated with paediatric inguinal hernias.
  • Further research is needed to understand the mechanisms behind these associations.
Abstract

More Related Videos

Quantification of Levator Ani Hiatus Enlargement by Magnetic Resonance Imaging in Males and Females with Pelvic Organ Prolapse07:41

Quantification of Levator Ani Hiatus Enlargement by Magnetic Resonance Imaging in Males and Females with Pelvic Organ Prolapse

Published on: April 17, 2019

10.1K
Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice05:24

Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice

Published on: October 10, 2025

5

Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
783
Varicose Veins I: Introduction01:26

Varicose Veins I: Introduction

Varicose veins, or varicosities, are abnormally dilated and twisted superficial veins caused by venous valve incompetence. This condition commonly affects the lower extremities, especially the saphenous veins, due to the higher pressure from prolonged standing and walking. However, varicosities can also occur in other areas, such as the esophagus, vulva, spermatic cords, and anorectal region.Etiology and typesPrimary varicose veins, often idiopathic, are more common in women due to inherent...
43
Mitral Valve Prolapse III: Nursing Management01:19

Mitral Valve Prolapse III: Nursing Management

The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
57
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
2.1K
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
12.8K
Anatomy of the Intestines01:23

Anatomy of the Intestines

Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
84.2K