Related Experiment Video
Updated: Oct 16, 2025
05:24
Modeling Ascending Vaginal Infection, Preterm Birth, and Neonatal Morbidity in Mice
Published on: October 10, 2025
5
Temporal Evolution of Maternal Mortality: 1980-2019.
Janete Vettorazzi1,2, Edimárlei Gonsales Valério1,2, Maria Alexandrina Zanatta1
1Department of Gynecology and Obstetrics, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Summary
Maternal deaths significantly decreased between 2000-2018 compared to earlier periods, with hypertension remaining a key cause. Infectious causes of maternal mortality saw a notable reduction.
Area of Science:
- Obstetrics and Gynecology
- Public Health
- Epidemiology
Background:
- Maternal mortality remains a critical public health concern globally.
- Understanding trends in maternal deaths is crucial for improving healthcare interventions.
- Previous studies at Hospital de Clínicas de Porto Alegre (HCPA) documented maternal mortality rates and causes.
Purpose of the Study:
- To analyze the profile of maternal deaths at HCPA between 2000 and 2019.
- To compare contemporary maternal death data with historical data from 1980-1999.
- To identify changes in causes and rates of maternal mortality over two decades.
Main Methods:
- A retrospective study of 2,481 medical records of women aged 10-49 who died between 2000 and 2018.
- Identification of maternal deaths occurring during pregnancy or postpartum.
- Comparison of findings with a previous study from the same institution.
Main Results:
- A maternal mortality ratio of 37.6 per 100,000 live births was observed.
- Hypertension during pregnancy (31.2%) and acute liver steatosis (25%) were the leading causes of maternal death.
- A significant decrease in maternal deaths due to infectious causes was noted compared to the 1980-1999 period.
Conclusions:
- There has been a substantial reduction in maternal mortality at HCPA.
- Infectious causes of maternal death have significantly decreased.
- Hypertensive disorders remain a primary concern in maternal mortality.
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