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Updated: Oct 16, 2025

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
The interaction of lipids and inflammatory markers predict negative symptom severity in patients with schizophrenia
David R Goldsmith1, Nicholas Massa2, Brian J Miller3
1Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, USA. drgolds@emory.edu.
Abstract:
Finding biological predictors and novel mechanisms underlying negative symptoms of schizophrenia is of significant importance given the lack of effective treatments. Increasing data support a role for metabolic dysfunction and inflammation in reward processing deficits in psychiatric illness. Herein, we found an interaction between lipids and inflammation as a predictor of worse negative symptom severity in individuals with schizophrenia. Future studies may seek to further elucidate this relationship and thereby reveal novel treatment targets for negative symptoms.
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