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Fluorescence Live-cell Imaging of the Complete Vegetative Cell Cycle of the Slow-growing Social Bacterium Myxococcus xanthus
Published on: June 20, 2018
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Complete Genome Sequence of Myxococcus Phage Mx4
1Institute of Integrative Biology, Department of Environmental Systems Science, ETH Zürich, Zürich, Switzerland.
Microbiology Resource Announcements
|October 21, 2021
Summary
The genomic sequence of Myxococcus xanthus phage Mx4 was determined. This bacteriophage belongs to the Myoviridae family, offering insights into microbial evolution.
Area of Science:
- Microbiology
- Virology
- Genomics
Background:
- Myxococcus xanthus is a key bacterial model organism.
- Understanding bacteriophages is crucial for microbial ecology and evolution.
Purpose of the Study:
- To present the complete genomic sequence of the wild-type Myxococcus phage Mx4.
- To classify the phage based on its genomic and protein characteristics.
Main Methods:
- Whole-genome sequencing of Myxococcus phage Mx4.
- Bioinformatic analysis for gene prediction and functional annotation.
- Phylogenetic classification based on conserved protein domains.
Main Results:
- The 57.0-kb circular genome of Myxococcus phage Mx4 was sequenced.
- A GC content of 70.1% was determined.
- Annotation revealed 97 predicted protein-coding genes.
- Mx4 was classified as a tailed phage, belonging to the Mu-like members of the Myoviridae family (group type 1, cluster 8).
Conclusions:
- The genomic data provides a foundational resource for Myxococcus phage Mx4.
- Classification places Mx4 within the Myoviridae family, aiding comparative genomics.
- This work contributes to the understanding of phage diversity and Myxococcus xanthus-phage interactions.
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