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SARS-CoV-2 in a Neonate with Truncus Arteriosus: Management and Surgical Correction Timing
M Masci1, P Moras2, L Di Chiara3
1Perinatal Cardiology Unit, Department of Medical and Surgical for Fetus-Neonate, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. marco.masci@opbg.net.
Pediatric Cardiology
|October 21, 2021
Summary
This case study highlights the surgical repair of congenital heart disease (CHD) in a newborn with Truncus Arteriosus, who also contracted SARS-CoV-2. The successful surgery was performed after COVID-19 recovery, demonstrating a viable treatment approach for high-risk infants.
Area of Science:
- Pediatric Cardiology
- Infectious Diseases
- Neonatal Surgery
Background:
- Congenital Heart Disease (CHD) and SARS-CoV-2 infection pose significant risks, particularly in newborns.
- Optimal surgical timing for CHD in neonates with concurrent SARS-CoV-2 infection remains unclear due to limited evidence and guidelines.
Observation:
- A newborn diagnosed with Truncus Arteriosus (TA) type A1 developed heart failure symptoms shortly after contracting SARS-CoV-2 from their father.
- Treatment involved diuretics and milrinone for heart failure, with observed reductions in N-terminal-pro hormone BNP levels.
Findings:
- The patient underwent successful surgical repair using Cardiopulmonary Bypass (CPB) 14 days after SARS-CoV-2 nasopharyngeal swab negativization.
- This represents the first reported case of surgical correction for CHD in a 40-day-old infant post-SARS-CoV-2 infection and negativization.
Implications:
- This case provides valuable insights into managing and surgically treating complex CHD in neonates with recent SARS-CoV-2 infection.
- It supports a symptom-based or PCR-based approach for determining surgical readiness in such high-risk pediatric patients.
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