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Host factors subverted by Mycobacterium tuberculosis: Potential targets for host directed therapy

Rashi Kalra1, Drishti Tiwari1, Hedwin Kitdorlang Dkhar1

  • 1Department of Molecular Biology, CSIR-Institute of Microbial Technology, Chandigarh-160036, India.

International Reviews of Immunology
|October 22, 2021
PubMed
Summary

Host-directed therapies (HDTs) offer new ways to fight tuberculosis (TB) by targeting host molecules exploited by Mycobacterium tuberculosis. Neutralizing these subverted host factors is key to developing better TB treatments.

Keywords:
Host directed therapy (HDT)host epigenetic machineryhost transcription factors (TFs)host-pathogen interactiontuberculosis (TB)

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