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Updated: Oct 16, 2025

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Surgical Approach and Complications of Stand-alone Lateral Trans-Psoas Interbody Fusion
Published on: February 14, 2025
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Single-position prone lateral transpsoas approach: early experience and outcomes
Journal of Neurosurgery. Spine
|October 22, 2021
Summary
Single-position prone lateral lumbar interbody fusion (LLIF) is a safe and effective minimally invasive technique. This study shows acceptable clinical and radiographic outcomes, with significant functional improvement in patients.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Spinal Fusion
Background:
- Minimally invasive lateral lumbar interbody fusion (LLIF) is commonly used for lumbar arthrodesis.
- Single-position surgery, avoiding patient repositioning, is gaining interest.
- Prone transpsoas LLIF allows access to anterior and posterior spine in one position.
Purpose of the Study:
- To evaluate the feasibility and outcomes of single-position prone transpsoas LLIF.
- To present a consecutive case series of patients undergoing this novel technique.
Main Methods:
- Retrospective review of adult patients undergoing single-position prone LLIF (Oct 2019-Nov 2020).
- Data collected included operative details, complications, and 3-month clinical outcomes.
- Radiographs assessed for intraoperative and postoperative interbody subsidence.
Main Results:
- 28 of 29 patients (97%) successfully treated with prone lateral approach.
- Mean age 67.9 years; 75% female; 39 levels treated.
- Significant improvement in Oswestry Disability Index, SF-36, and VAS pain scores.
Conclusions:
- Single-position prone LLIF is well-tolerated with acceptable outcomes.
- Further research with larger series and longer follow-up is needed to confirm safety and long-term results.

