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Updated: Oct 15, 2025
Adipo-Clear: A Tissue Clearing Method for Three-Dimensional Imaging of Adipose Tissue
Published on: July 28, 2018
Subcutaneous adipose tissue thickness around the ASIS area for human body models in reclined positions
Sylvia Schick1, Julia Muehlbauer1, Anja Wagner1
1Biomechanics and Accident Analysis, Institute of Legal Medicine, Ludwig-Maximilians University Munich (LMU), Germany.
Objective:
Subcutaneous adipose tissue (SAT) thickness above the anterior superior iliac spine (ASIS) influences belt fit of a vehicle occupant. To improve finite element (FE) human body models and their application assessing future seating positions in cars, there is a need for more detailed data.
Methods:
Anthropometric input data were used to statistically model a lower limit of the SAT thickness in the area around the ASIS (at the ASIS or in the groin) extracted from 102 postmortem computed tomography (pmCT) data sets (56 males and 46 females). Additionally, 2 pmCT scans of 1 male individual in both supine and sitting conditions were used to estimate change in SAT thickness by position.
Results:
Distributions and locations of minimum values for SAT thickness were derived for males and females. Sex, age, and body mass index (BMI) remained in a linear regression model for the minimum SAT thickness in the ASIS area. Thirty-seven percent of the variance in the SAT distribution of the sample can be explained by these input variables. The individual with data in supine and sitting positions showed an SAT thickness value above the ASIS 6 times higher in the sitting position than in the supine position.
Conclusions:
Individual factors influence SAT thickness around the ASIS in addition to BMI, sex, and age. The presented values need to be regarded as a lower limit of SAT thickness, because in 63% the minimum was found in the groin area and the measurements were performed in a supine position. The increase in SAT thickness in a sitting position compared to supine seen in the case example shows the need for further data acquisition to establish a transfer function interpolating between both positions. The SAT thickness minimum values in the ASIS area shown in this study can provide valuable input for soft tissue modeling in human body models with the aim to analyze seat belt fit and to computationally assess lap belt and occupant interaction sensitivity to SAT tissue thickness under load. This might be crucial in reclined sitting positions in automated driving.
