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Comparisons of two definitions of bronchopulmonary dysplasia for the premature infants

Jiahui Li1, Haiyan Xu1,2

  • 1Department of Pediatrics, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.

Pediatric Pulmonology
|October 23, 2021
PubMed

Insights

The Jensen definition of bronchopulmonary dysplasia (BPD) in premature infants better correlates with health expenditures than the Workshop definition. This finding impacts understanding of BPD

Area of Science:

  • Neonatal Medicine
  • Pediatric Pulmonology
  • Health Economics

Background:

  • Bronchopulmonary dysplasia (BPD) is a common respiratory complication in premature infants.
  • Current definitions of BPD lack universal consensus, leading to varied clinical and economic assessments.

Purpose of the Study:

  • To compare clinical outcomes and health economic expenditures using two different definitions of BPD: the National Institute of Health and Human Development (Workshop) definition and the Jensen definition.
  • To evaluate the correlation between BPD definitions and healthcare costs in premature infants.

Main Methods:

  • A cohort of premature infants (≤32 weeks gestational age) admitted to the NICU between January 2018 and January 2020 was analyzed.
  • Clinical consequences and health economic expenditures were assessed based on the Workshop and Jensen definitions of BPD.
  • 303 survivors were evaluated at 36 weeks postmenstrual age.

Main Results:

  • Bronchopulmonary dysplasia (BPD) prevalence was 47.5% using the Workshop definition and 37.6% using the Jensen definition.
  • The Jensen definition showed a significantly stronger correlation with NICU charges compared to the Workshop definition.
  • Unclassified BPD rates were 0.9% (Workshop) and 3.3% (Jensen).

Conclusions:

  • The Jensen definition of BPD demonstrates a better correlation with health expenditures than the Workshop definition.
  • This suggests the Jensen definition may provide a more accurate reflection of the economic burden associated with BPD in premature infants.
Abstract

Keywords:
bronchopulmonary dysplasiadefinitionneonatal intensive care unit

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