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Updated: Oct 15, 2025

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Gasless Endoscopic Thyroidectomy via the Trans-Axillary Approach
Published on: September 15, 2023
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Transaxillary gasless endoscopic thyroidectomy versus conventional open thyroidectomy: systematic review and
Kristijonas Jasaitis1, Anna Midlenko2, Aigerim Bekenova2
1Department of Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Summary
Endoscopic transaxillary gasless thyroidectomy (ET) offers reduced postoperative pain compared to open thyroidectomy (OT) with similar complication rates. While ET requires longer surgery times, it is a safe and feasible alternative.
Area of Science:
- Surgical Oncology
- Minimally Invasive Surgery
- Endocrine Surgery
Background:
- Conventional open thyroidectomy (OT) is a standard surgical approach.
- Endoscopic transaxillary gasless thyroidectomy (ET) is an alternative minimally invasive technique.
- Comparative data on surgical outcomes and safety between OT and ET are limited.
Purpose of the Study:
- To systematically review and meta-analyze surgical outcomes and safety of conventional open thyroidectomy (OT) versus endoscopic transaxillary gasless thyroidectomy (ET).
Main Methods:
- Systematic literature search conducted.
- Weighted mean differences and odds ratios with 95% CIs analyzed for outcomes and complications.
- Fixed- or random-effects models used for analysis.
- Heterogeneity assessed using Cochran Q test and I² statistic.
Main Results:
- Ten studies involving 1597 patients were included.
- Endoscopic transaxillary gasless thyroidectomy (ET) was associated with significantly longer operative times.
- Postoperative pain was significantly lower on day 1 and day 7 after ET.
- No significant difference in complication rates between ET and OT was observed.
Conclusions:
- Endoscopic transaxillary gasless thyroidectomy (ET) is a feasible and safe procedure with the advantage of reduced postoperative pain compared to open thyroidectomy (OT).
- Longer operative time is a disadvantage of ET.
- Further high-quality prospective randomized studies are needed for definitive conclusions.

