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Functional hydrogel coatings.

Junjie Liu1, Shaoxing Qu1, Zhigang Suo2

  • 1Center for X-Mechanics, Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province and Department of Engineering Mechanics, Zhejiang University, Hangzhou 310027, China.

National Science Review
|October 25, 2021
PubMed
Summary

Functional hydrogel coatings offer enhanced biocompatibility and adhesion for medical devices. This review covers their applications, coating methods, and adhesion testing for improved tissue integration.

Keywords:
adhesioncoating methodscoating testshydrogel applicationshydrogel coatings

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Surface Engineering

Background:

  • Hydrogels, natural or synthetic polymer networks, exhibit excellent biocompatibility and tunable mechanical, chemical, and electrical properties.
  • Since the 1960s, hydrogels have been extensively researched for medical applications, notably contact lenses.
  • Recent advancements include functional hydrogel coatings with controlled thickness and robust adhesion on diverse substrates.

Purpose of the Study:

  • To review the applications and functions of functional hydrogel coatings.
  • To discuss methods for coating various substrates with functional hydrogels, emphasizing tough adhesion.
  • To summarize tests for evaluating the adhesion between hydrogel coatings and substrates.

Main Methods:

  • Review of existing literature on hydrogel coating technologies.
  • Analysis of different hydrogel materials and substrate types.
  • Examination of adhesion testing methodologies for hydrogel-substrate interfaces.

Main Results:

  • Hydrogel-coated substrates integrate hydrogel benefits (lubricity, biocompatibility, anti-fouling) with substrate advantages (stiffness, strength).
  • Various coating techniques enable controlled thickness and strong adhesion for diverse applications.
  • Standardized adhesion tests are crucial for validating coating performance.

Conclusions:

  • Functional hydrogel coatings represent a significant advancement in biomaterials, enhancing medical device performance.
  • Further research into robust coating methods and reliable adhesion testing will drive innovation.
  • These coatings hold promise for improved biocompatibility and integration in biomedical applications.