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Published on: September 16, 2022
Antifungal-Loaded Calcium Sulfate Beads as a Potential Therapeutic in Combating Candida auris
Mark C Butcher1, Jason L Brown1, Donald Hansom1,2
1Oral Sciences Research Group, Glasgow Dental School, School of Medicine, Dentistry and Nursing, College of Medical, Veterinary and Life Sciences, University of Glasgowgrid.8756.c, Glasgow, UK.
Abstract:
Candida auris provides a substantial global nosocomial threat clinically. With the recent emergence that the organism can readily colonize skin niches, it will likely continue to pose a risk in health care units, particularly to patients undergoing surgery. The purpose of this study was to investigate the efficacy of antifungal-loaded calcium sulfate (CS) beads in combatting C. auris infection. We demonstrate that the CS-packed beads have the potential to interfere with planktonic and sessile C. auris.
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