[Radiofrequency Ablation for Lung Ground-glass Nodule]

Area of Science:

• Pulmonology
• Oncology
• Interventional Radiology

Background:

• Computed tomography (CT) screening detects increasing numbers of lung ground glass nodules (GGNs).
• Early intervention for lung nodules improves patient survival rates.
• Radiofrequency ablation (RFA) offers a minimally invasive option for lung malignancies.

Purpose of the Study:

• To evaluate the safety and clinical efficacy of RFA for treating lung GGNs.

Main Methods:

• 28 lung GGNs in 24 patients were treated with RFA between June 2016 and March 2021.
• Procedures involved 28 RFA sessions with an average ablation range of 2.50 cm and duration of 15 minutes.
• Patient demographics included 13 males and 11 females, with an average age of 69.4 years.

Main Results:

• All RFA procedures were completed without perioperative deaths or serious complications.
• The median follow-up period was 25 months.
• A 100% local control rate was observed for all 28 GGNs, with 1- and 2-year overall survival rates of 95.8% and tumor-specific survival rates of 100%.

Conclusions:

• Radiofrequency ablation (RFA) demonstrates safety and effectiveness for lung GGN treatment.
• RFA is a viable minimally invasive therapeutic option for lung GGNs.
• The study supports RFA as a promising technique for managing lung GGNs.