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High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses
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Mechanisms of inhibition of viral RNA replication by nucleotide analogs

Kenneth A Johnson1, Tyler Dangerfield1

  • 1Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, United States.

The Enzymes
|October 26, 2021
PubMed

Keywords:
CoronavirusEnzyme specificityNucleoside analogsPolymerase kineticsProofreading exonucleaseRNA-dependent RNA polymeraseRemdesivirSARS CoV-2Single-turnover kinetics

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