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Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
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Comparing SPEED and OSDI Questionnaires in a Non-Clinical Sample.

Nauman Hashmani1, Uzair Munaf2, Aqsa Saleem2

  • 1Ophthalmology and Visual Sciences, Hashmanis Hospital, Karachi, Sindh, Pakistan.

Clinical Ophthalmology (Auckland, N.Z.)
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Summary

The SPEED questionnaire is an effective alternative to the OSDI for assessing dry eye disease symptoms in Pakistan. This study validated SPEED

Keywords:
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Area of Science:

  • Ophthalmology
  • Public Health

Background:

  • Dry eye disease (DED) diagnosis often relies on patient-reported outcomes.
  • The Ocular Surface Disease Index (OSDI) is a common questionnaire for DED symptom assessment.
  • Evaluating alternative, validated instruments is crucial for diverse populations.

Purpose of the Study:

  • To compare the performance of the SPEED questionnaire against the OSDI in a non-clinical Pakistani population.
  • To assess the utility of the SPEED questionnaire as a screening tool for DED.

Main Methods:

  • A sample of 600 participants in Pakistan completed both SPEED and OSDI questionnaires.
  • Statistical analyses included Cronbach's alpha for reliability and receiver operating characteristic (ROC) curve analysis.
  • Mean SPEED scores were analyzed across OSDI severity categories.

Main Results:

  • Both OSDI (0.924) and SPEED (0.879) demonstrated high internal consistency.
  • The area under the ROC curve (AUC) was 0.791, indicating good diagnostic performance for SPEED.
  • A cutoff score of 4.00 on the SPEED questionnaire was identified as effective (P < 0.001).

Conclusions:

  • The SPEED questionnaire exhibits strong reliability and validity in a Pakistani non-clinical sample.
  • SPEED can serve as an effective and potentially more accessible alternative to the OSDI for DED symptom assessment in this population.