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Comparing SPEED and OSDI Questionnaires in a Non-Clinical Sample.
Nauman Hashmani1, Uzair Munaf2, Aqsa Saleem2
1Ophthalmology and Visual Sciences, Hashmanis Hospital, Karachi, Sindh, Pakistan.
Clinical Ophthalmology (Auckland, N.Z.)
|October 27, 2021
Summary
The SPEED questionnaire is an effective alternative to the OSDI for assessing dry eye disease symptoms in Pakistan. This study validated SPEED
Area of Science:
- Ophthalmology
- Public Health
Background:
- Dry eye disease (DED) diagnosis often relies on patient-reported outcomes.
- The Ocular Surface Disease Index (OSDI) is a common questionnaire for DED symptom assessment.
- Evaluating alternative, validated instruments is crucial for diverse populations.
Purpose of the Study:
- To compare the performance of the SPEED questionnaire against the OSDI in a non-clinical Pakistani population.
- To assess the utility of the SPEED questionnaire as a screening tool for DED.
Main Methods:
- A sample of 600 participants in Pakistan completed both SPEED and OSDI questionnaires.
- Statistical analyses included Cronbach's alpha for reliability and receiver operating characteristic (ROC) curve analysis.
- Mean SPEED scores were analyzed across OSDI severity categories.
Main Results:
- Both OSDI (0.924) and SPEED (0.879) demonstrated high internal consistency.
- The area under the ROC curve (AUC) was 0.791, indicating good diagnostic performance for SPEED.
- A cutoff score of 4.00 on the SPEED questionnaire was identified as effective (P < 0.001).
Conclusions:
- The SPEED questionnaire exhibits strong reliability and validity in a Pakistani non-clinical sample.
- SPEED can serve as an effective and potentially more accessible alternative to the OSDI for DED symptom assessment in this population.

