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A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants
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3D virtual reality vs. 2D desktop registration user interface comparison.

Andreas Bueckle1, Kilian Buehling2, Patrick C Shih3

  • 1Department of Intelligent Systems Engineering, Luddy School of Informatics, Computing, and Engineering, Indiana University, Bloomington, Indiana, United States of America.

Plos One
|October 27, 2021
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Summary
This summary is machine-generated.

The 2D Desktop interface is effective for registering human tissue blocks, offering comparable accuracy to virtual reality setups. This traditional method is also more practical and cost-effective for wet-bench environments.

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Area of Science:

  • Biomedical Imaging
  • Human Anatomy
  • Medical Informatics

Background:

  • Accurate spatial registration of human tissue is crucial for the Human Biomolecular Atlas Program (HuBMAP).
  • The Registration User Interface (RUI) was developed to aid in registering tissue blocks to reference organs.
  • Current RUI implementations are being evaluated for efficiency and accuracy.

Purpose of the Study:

  • To compare the performance of a 2D Desktop RUI implementation against two Virtual Reality (VR) RUI implementations (VR Tabletop and VR Standup).
  • To evaluate user accuracy, completion time, and satisfaction across the three RUI setups.
  • To determine the most suitable RUI setup for tissue block registration in HuBMAP.

Main Methods:

  • A user study was conducted with 42 participants comparing 2D Desktop, VR Tabletop, and VR Standup RUI setups.
  • Participants completed tasks involving the registration of 3D tissue blocks to reference organs.
  • Performance metrics included position accuracy, rotation accuracy, and task completion time.

Main Results:

  • VR users were significantly faster and more accurate in rotation compared to 2D Desktop users.
  • No significant differences in normalized position accuracy were found across the three setups.
  • Extrapolated 2D Desktop performance met expert needs for speed and accuracy, with added benefits of lower cost and ease of use.

Conclusions:

  • While VR offers advantages in speed and rotation accuracy, the 2D Desktop RUI is a practical, cost-effective, and suitable solution for tissue block registration in wet-bench environments.
  • The 2D Desktop setup meets the accuracy and speed requirements for experts in tissue dissection within the HuBMAP consortium.
  • Further research may explore hybrid approaches or specific use cases where VR's advantages are paramount.