Related Experiment Video
Updated: Oct 15, 2025

Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
Emerging Trends and Thematic Evolution of Breast Cancer: Knowledge Mapping and Co-Word Analysis
Ali Sadatmoosavi1, Oranus Tajedini2, Omid Esmaeili3
1Department of Medical Library & Information Sciences, Faculty of Management and Medical Information Sciences, Kerman University of Medical Sciences, Kerman, Iran.
This scientometric study maps breast cancer research evolution from 1988-2020, identifying key themes like radiation injury and antineoplastic agents. Findings offer a roadmap for future breast cancer research and policy.
Area of Science:
- Breast cancer research
- Scientometrics
- Science mapping
Background:
- A comprehensive understanding of a scientific discipline is essential for researchers.
- This study focuses on the field of breast cancer research.
Purpose of the Study:
- To create a science map of breast cancer research.
- To analyze the structure and evolution of breast cancer research.
- To identify emerging trends in breast cancer research publications.
Main Methods:
- A descriptive survey using a scientometric approach.
- Data sourced from MEDLINE using Medical Subject Heading (MeSH) terms.
- Science mapping employed to visualize interrelations and evolution over three periods (1988-2020).
Main Results:
- 12,577 scientometric records on breast cancer research were analyzed.
- Identified 8 core research themes: radiation injury, cardiovascular disease, fibroadenoma, antineoplastic agent, estrogen antagonistic, immunohistochemistry, soybean, and epitopes.
- Strategic diagrams revealed themes categorized by centrality and density, indicating their importance and development within the field.
Conclusions:
- Breast cancer research themes were classified into motor, peripheral, emerging/declining, and basic/transversal categories.
- Motor themes (e.g., stem cell, protein tyrosine kinase) are crucial for the field's structure.
- Scientometric analysis provides a valuable roadmap for future breast cancer research and policy-making.
More Related Videos
Related Concept Videos
Cancer Survival Analysis
mTOR Signaling and Cancer Progression
The mTOR pathway or the...
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Cancer-Critical Genes II: Tumor Suppressor Genes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Current Trends in Nursing I

