First step in assessment of VipGrade^®, a computerized clinical decision system to assess Vipera envenomation grading:...

We conducted a retrospective review of Vipera spp. snakebite cases registered by the PCC of Bordeaux, France, between January 1, 2018, and December 31, 2020, evaluating the agreement between VipGrade^® assessments, toxicologists' assessments, and current guidelines.

133 patients with Vipera aspis snakebites were included. There was 100% agreement in severity grading by PCC guidelines and VipGrade^®. However, grading by toxicologists and VipGrade^® diverged in 19 cases (85% agreement; κ = 0.80; 95% CI: 0.71 to 0.87).

The VipGrade^® tool's grading reflects current PCC guidelines, which are authoritative in France, and may allow for a more rapid and standardized determination of management and follow-up of viper-bitten patients. It should be noted, however, that the more complex and dynamic aspects of management are not included in VipGrade^®. Its purpose is to supplement, not replace, the advice of the PCC's clinical toxicologists, and this advice should be sought whenever a viper bite is encountered in clinical practice.