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Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

52
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
52
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

48
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
48
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

38
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
38
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

41
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
41

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Related Experiment Video

Updated: Oct 15, 2025

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
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Hemodynamic changes after intracranial aneurysm growth.

Bart M W Cornelissen1,2,3, Eva L Leemans1,2, Cornelis H Slump3

  • 11Department of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam.

Journal of Neurosurgery
|October 29, 2021
PubMed
Summary

Aneurysm growth significantly alters hemodynamics, with wall shear stress decreasing on average. These changes in hemodynamic characteristics vary greatly between individual aneurysms, impacting rupture risk assessment.

Keywords:
aneurysm growthcomputational fluid dynamicshemodynamicsintracranial aneurysmvascular disorders

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Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Computational Fluid Dynamics

Background:

  • Accurate risk assessment of unruptured intracranial aneurysms is crucial.
  • Hemodynamic factors are known to influence aneurysm growth and rupture.
  • The impact of aneurysm growth on hemodynamics remains unclear.

Purpose of the Study:

  • To investigate how hemodynamic characteristics change during intracranial aneurysm growth.
  • To assess the relationship between aneurysm growth and metrics like wall shear stress.

Main Methods:

  • Longitudinal MRA data from 25 patients (31 aneurysms) with observed growth were analyzed.
  • Patient-specific vascular models were created for baseline and follow-up.
  • Computational fluid dynamics (CFD) computed intra-aneurysmal hemodynamics (wall shear stress, OSI, low shear area).

Main Results:

  • Aneurysm volume increased by a median of 26 mm³ over a mean of 4 years.
  • Median wall shear stress significantly decreased post-growth.
  • Other hemodynamic parameters showed high individual variability despite no significant average change.

Conclusions:

  • Intracranial aneurysm growth leads to considerable changes in hemodynamic characteristics.
  • Wall shear stress generally decreases after aneurysm growth.
  • Significant variability exists in hemodynamic changes, highlighting the complexity of aneurysm rupture risk.