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Updated: Oct 15, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Congenital lung lesions: a radiographic pattern approach
Alexander Maad El-Ali1, Naomi A Strubel2, Shailee V Lala2
1Division of Pediatric Radiology, Department of Radiology, NYU Grossman School of Medicine, 550 First Ave., New York, NY, 10016, USA. alexander.el-ali@nyulangone.org.
Diagnosing congenital lung malformations in newborns is challenging due to overlapping imaging features. Recognizing key radiographic patterns like hyperlucent lung and pulmonary cysts aids in differential diagnosis.
Area of Science:
- Pediatric Radiology
- Thoracic Imaging
- Congenital Abnormalities
Background:
- Congenital lung malformations (CLMs) are diverse and can present with similar imaging findings.
- Neonatal diagnosis of CLMs poses challenges due to overlapping appearances and co-occurrence.
Purpose of the Study:
- To review the multimodality imaging features of common CLMs.
- To categorize CLMs based on archetypal radiographic patterns.
- To highlight important imaging mimickers of CLMs.
Main Methods:
- Review of multimodality imaging (e.g., radiography, CT, MRI) of congenital lung malformations.
- Categorization of malformations based on four primary radiographic archetypes: hyperlucent lung, pulmonary cysts, focal opacity, and normal radiograph.
- Inclusion of common imaging mimickers for comparative analysis.
Main Results:
- Archetypal radiographic patterns can significantly narrow the differential diagnosis for neonatal lung abnormalities.
- Specific imaging features are associated with distinct congenital lung malformations within each archetype.
- Recognition of imaging mimickers is crucial to avoid misdiagnosis.
Conclusions:
- Understanding archetypal radiographic patterns is essential for accurate diagnosis of congenital lung malformations in neonates.
- Multimodality imaging review, categorized by pattern, aids in differentiating CLMs and their mimics.
- This approach improves diagnostic accuracy in challenging neonatal thoracic imaging cases.
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