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Updated: Oct 14, 2025

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
Neurofibromatosis Type I and Stromal Tumor with a Multiple Digestive Localization
Amina Chaka1, Farouk Ennaceur1, Mohamed Amine Tormen1
1Department of General and Digestive Surgery at the University Hospital Fattouma Bourguiba of Monastir, University of Monastir, Tunisia.
Abstract:
Neurofibromatosis type I (NF1) is also known as von Recklinghausen disease. It is a genetic disorder that affects the growth and development of nerve cell tissue, which is characterized by a multisystem disorder and an increased risk for cancer. The incidence of gastroduodenal stromal tumor during Recklinghausen disease can reach 35% in autopsies and 5% in clinical cases. In our case, the diagnosis of neurofibromatosis type I was made in a middle-aged women initially diagnosed with a pancreaticoduodenal tumor.

