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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Skin Cancer01:30

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Classification of Epithelial Tissues: Overview01:22

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Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
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Classification of Systems-II01:31

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Continuous-time systems have continuous input and output signals, with time measured continuously. These systems are generally defined by differential or algebraic equations. For instance, in an RC circuit, the relationship between input and output voltage is expressed through a differential equation derived from Ohm's law and the capacitor relation,
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Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Related Experiment Video

Updated: Oct 14, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

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Cutaneous and Systemic Psoriasis: Classifications and Classification for the Distinction.

Bing-Xi Yan1, Xue-Yan Chen1, Li-Ran Ye1

  • 1Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Frontiers in Medicine
|November 1, 2021
PubMed
Summary

Psoriasis, a chronic inflammatory condition affecting 0.1-1.5% globally, presents with skin plaques and potential systemic comorbidities. This review proposes classifying it as cutaneous or systemic psoriasis for improved understanding and management.

Keywords:
biologicsclassification criteriacutaneous and systemicdiagnosispsoriasistherapy

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Area of Science:

  • Immunology
  • Dermatology
  • Systemic Inflammatory Diseases

Background:

  • Psoriasis affects 0.1-1.5% of the global population.
  • Characterized by scaly, erythematous plaques, it is a chronic multisystem inflammatory disease.
  • Associated comorbidities include psoriatic arthritis, metabolic syndrome, cardiovascular disease, and neurological conditions.

Purpose of the Study:

  • To propose a novel classification system for psoriasis.
  • To distinguish between cutaneous and systemic manifestations.
  • To enhance the understanding and management of psoriasis.

Main Methods:

  • Literature review and synthesis of existing research.
  • Analysis of clinical presentations and associated comorbidities.
  • Development of a proposed classification framework.

Main Results:

  • Psoriasis exhibits both classic cutaneous and broader systemic involvement.
  • A clear distinction between cutaneous and systemic psoriasis is proposed.
  • The proposed classification aims to improve diagnostic and therapeutic approaches.

Conclusions:

  • Psoriasis is more than a skin condition, often involving multiple organ systems.
  • Classifying psoriasis as cutaneous or systemic psoriasis offers a clearer framework.
  • This classification can guide clinical practice and future research for better patient outcomes.