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Updated: Oct 14, 2025
06:34
A Bioinformatics Pipeline to Accurately and Efficiently Analyze the MicroRNA Transcriptomes in Plants
Published on: January 21, 2020
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GreeNC 2.0: a comprehensive database of plant long non-coding RNAs
Marco Di Marsico1, Andreu Paytuvi Gallart2, Walter Sanseverino2
1Dipartimento di Scienze Agrarie, Alimentari e Ambientali, Università degli Studi di Perugia, Borgo XX Giugno 74, 06121 Perugia, Italy.
Nucleic Acids Research
|November 1, 2021
Summary
The updated Green Non-Coding Database (GreeNC) now annotates over 495,000 plant long non-coding RNAs (lncRNAs) across 94 species, aiding research into their function and evolution.
Area of Science:
- Plant biology
- Genomics
- Bioinformatics
Background:
- Long non-coding RNAs (lncRNAs) play crucial roles in plant gene regulation.
- The Green Non-Coding Database (GreeNC) is a key resource for studying plant lncRNAs.
- Previous versions of GreeNC have provided valuable lncRNA annotations.
Purpose of the Study:
- To present the latest update of the GreeNC database.
- To expand the annotation of plant lncRNAs with new species and updated information.
- To provide insights into lncRNA sequence conservation and gene families.
Main Methods:
- Updating annotations for 16 plant species.
- Adding annotations for 78 new plant species.
- Performing sequence clustering to analyze lncRNA conservation and identify gene families.
Main Results:
- The GreeNC database now includes annotations for over 495,000 lncRNAs.
- The database covers a total of 94 plant species.
- Sequence clustering revealed information on sequence conservation and gene families.
Conclusions:
- The expanded GreeNC database represents a significant advancement in plant lncRNA research.
- This updated resource facilitates comparative genomics and functional studies of plant lncRNAs.
- GreeNC continues to be an essential tool for the plant science community.
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