COMPARATIVE EVALUATION OF HISTOTOXICITY INDICATORS OF METAL ALLOYS FOR THE MANUFACTURE OF METAL CERAMIC DENTAL...

Area of Science:

• Biomaterials Science
• Dental Materials
• Histopathology

Background:

• Metal-ceramic restorations are common in dentures.
• Assessing the histotoxicity of implantable metal alloys is crucial for patient safety.
• Understanding tissue response to dental alloys informs material selection.

Purpose of the Study:

• To comparatively assess the histotoxicity of various metal alloys used in metal-ceramic denture constructions.
• To determine the impact of different alloy compositions on subcutaneous tissue healing.

Main Methods:

• Experimental-morphological study involving implantation of standard metal alloy samples.
• Histological analysis of tissue capsules formed around implanted alloys over two experimental periods.
• Evaluation of healing time and connective tissue formation.

Main Results:

• Significant differences in subcutaneous tissue healing times were observed among the tested alloys.
• "Remanium-2000" (cobalt-based) and "Shot-alloy" demonstrated the most complete healing with mature fibrous connective tissue formation.
• "Cerium" alloy also showed favorable healing outcomes.

Conclusions:

• The histotoxicity and healing response to implanted metal alloys are influenced by their specific chemical composition and combinations.
• Cobalt-based alloys, such as "Remanium-2000", show promising biocompatibility for dental applications.
• Further research into alloy composition and tissue interaction is warranted.