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Updated: Oct 14, 2025

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Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo
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A 20-year split-mouth comparative study of two screw-shaped titanium implant systems
International Journal of Oral Implantology (Berlin, Germany)
|November 2, 2021
Summary
This 20-year study found clinically insignificant marginal bone loss around screw-shaped titanium implants. Both Astra Tech and Brånemark implant types showed similar survival rates and minimal bone loss over time.
Area of Science:
- Dental Implantology
- Periodontology
- Biomaterials Science
Background:
- Dental implants are a common solution for tooth replacement.
- Long-term data on implant performance is crucial for clinical decision-making.
- Assessing marginal bone loss and survival rates helps evaluate implant longevity.
Purpose of the Study:
- To compare marginal bone loss and implant survival between Astra Tech (group A) and Brånemark (group B) implants.
- To prospectively evaluate these outcomes over a 20-year follow-up period.
- To conduct a split-mouth study for direct comparison within patients.
Main Methods:
- A total of 95 implants (50 group A, 45 group B) were randomly placed in 18 patients.
- Clinical and radiographic examinations were performed at 5, 10, 15, and 20 years post-prosthesis insertion.
- Split-mouth design allowed for direct comparison of implant types within the same patient.
Main Results:
- Ten patients completed the 20-year follow-up (26 group A, 25 group B implants).
- No implant loss or prosthetic failures were recorded.
- No significant differences in marginal bone loss were observed between implant groups (P=0.25) or over time (P≥0.05).
Conclusions:
- Screw-shaped titanium implants demonstrate clinically insignificant marginal bone loss after 20 years.
- Astra Tech and Brånemark implants exhibited comparable survival rates and marginal bone loss over the 20-year follow-up.
- The study supports the long-term efficacy and predictability of both implant systems.

