Evolution of Hematological Parameters in Patients Undergoing Orthognathic Surgery With a View to Hospital Discharge:...

The length of hospital stays of patients undergoing orthognathic surgery depends on related local and systemic factors. Hematological changes resulting from orthognathic surgery, followed up in the postoperative period until hospital discharge, have neither yet been established for specific cases, nor for normal situations. This study aimed to describe the hemodynamic parameters of patients undergoing orthognathic surgery, considering a prediction of hospital discharge. A prospective analytical study was carried out on a sample of convenience for this purpose.

The erythrogram, leukogram, and platelet count were assessed 24 and 72 hours after surgery and compared with preoperative values. Intraoperative volume loss was also assessed. Inferential statistical analyses were performed as analysis of variance or Friedman test, paired Wilcoxon test, Mann-Whitney test, and 2-tailed Spearman correlation.

The red blood cell count (mean ± standard deviation [median]); (4.60 ± 0.24 [4.56]), hemoglobin (12.82 ± 1.03 [12.75]), hematocrit (39.51 ± 3.47 [39.60]), and red cell distribution with (32.60 ± 0.88 [33.05]) were higher preoperatively (P < 0.001). Mean corpuscular volume (83.87 ± 5.63 [83.10]), mean corpuscular hemoglobin (27.50 ± 1.47 [28.00]), leukocytes (6262.00 ± 1448.36 [6380.00]). The volume loss varied between 463.87 and 752.13 mL (608.00 ± 144.13 [630.00]).

The results of the hematological evaluations corroborate the expectation of standard discharge from the hospital, with reflected changes resulting from volume loss and intense postoperative inflammatory response, even under the anti-inflammatory pharmacological effect.