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Updated: Oct 14, 2025
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Published on: November 15, 2019
Silicone allergy associated with intraocular silicone ball prosthesis in a dog
Yuichiro Muramatsu1, Usio Fukushima1, Soroku Kudo1
1Ophthalmology (Muramatsu, Fukushima, Kudo), Oncology (Ono), and Cardiology (Hirao), Japan Animal Referral Medical Center, 2-5-8 Kuji, Takatsu-ku, Kawasaki-shi, Kanagawa 213-0032, Japan and Akatsuka Dog & Cat Hospital (Akatsuka), 5-6-21 Kitaterao, Tsurumi-ku, Yokohama-shi, Kanagawa 234-0074, Japan.
Abstract:
A 13-year-old, male Pomeranian dog was presented for scleral rupture with intraocular hemorrhage and retinal detachment in the right eye. After intrascleral silicone ball prosthesis, recurrent swelling and granulomatous blepharitis were observed for 140 d and finally melting keratitis developed. Although an intraorbital prosthesis was implanted, recurrent, serious, erosive, and ulcerative blepharitis developed with high plasma C-reactive protein concentrations. Since the blepharitis could not be controlled, the silicone ball was removed and the affected orbit was debrided. The blepharitis resolved rapidly, and the orbit healed routinely. Positive allergic reactions to silicone were discovered through a patch test. Key clinical message: To the authors' knowledge, this is the first report on silicone allergy in a dog with positive allergic reactions to silicone in the patch test.
