Related Experiment Video
Updated: Oct 14, 2025

Apparatus for Harvesting Tissue Microcolumns
Published on: October 25, 2018
Cytrellis: A Novel Microcoring Technology for Scarless Skin Removal: Summary of Three Prospective Clinical Trials
Jason N Pozner1,2, Suzanne L Kilmer3, Roy G Geronemus4
1Sanctuary Plastic Surgery, Boca Raton, Fla.
Background:
We introduce an innovative and novel technology that achieves scarless skin removal without the use of thermal energy. Microcoring technology (MCT) uses a modified, hollow hypodermic needle to remove skin safely and without a scar. This method is advantageous compared to other fractional devices, given that it has the same benefits as energy-based devices (removal of skin cores without a scar), with the added value of immediate closure along the relaxed skin tension lines, with significantly less thermal energy.
Methods:
Three prospective clinical safety trials analyzing MCT treatment on abdominal and facial skin (short- and long-term) are described.
Results:
MCT treatment of human skin resulted in scarless skin removal that was well tolerated by patients. Healing occurred rapidly, with limited side effects. Skin area reduction (skin tightening) and increase in skin thickness were observed long term.
Conclusions:
MCT treatment of human skin is safe and well tolerated. Although further studies on efficacy are required to evaluate the full potential of MCT in skin rejuvenation, early findings such as skin tightening and increase in skin thickness are encouraging.
More Related Videos
07:29Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
09:37Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Tissue Renewal without Stem Cells
However, failure of such a system...
Confocal Fluorescence Microscopy
Renewal of Skin Epidermal Stem Cells
Clinical Trials: Overview