Related Experiment Video
Updated: Jun 18, 2026
10:41
A Tuberculosis Molecular Bacterial Load Assay (TB-MBLA)
Published on: April 30, 2020
Microcoring
Ilana D Breen1, Keemberly Kim2, Bridget Myers3
1Department of Dermatology, University of California, Irvine Dermatology, 118 Med Surg 1 Building. 810, Irvine, CA 92697, USA.
Dermatologic Clinics
|June 16, 2026
Summary
Microcoring, a novel skin treatment, uses hollow needles and suction to remove skin columns, promoting healing. This minimally invasive technique offers a safe alternative for skin rejuvenation and scar revision, especially in diverse skin tones.
Area of Science:
- Dermatology
- Cosmetic Surgery
- Regenerative Medicine
Background:
- Microcoring is a minimally invasive procedure for skin rejuvenation.
- It involves mechanical removal of skin columns using hollow needles and vacuum suction.
- The technique aims to induce scarless healing and dermal remodeling.
Purpose of the Study:
- To evaluate the clinical promise of microcoring for various dermatological applications.
- To highlight its mechanism of action, including excess skin removal and dermal remodeling.
- To compare its safety profile with energy-based devices, particularly for skin of color.
Main Methods:
- Utilizes hollow needles connected to vacuum suction.
- Mechanically removes precise columns of skin.
- Induces a scarless healing response.
Main Results:
- Demonstrated clinical efficacy in rhytid reduction, skin rejuvenation, and scar revision.
- Offers an improved safety profile due to the absence of heat.
- Shows particular promise for individuals with skin of color.
Conclusions:
- Microcoring is a safe and effective option for cosmetic and reconstructive procedures.
- Presents a viable alternative to more invasive surgical interventions.
- Its unique mechanism supports its role in advanced skin treatments.
Related Concept Videos
01:24Microbial Corrosion
Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...
01:29Microbial Morphologies
Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...
01:22Microenvironments
Microorganisms inhabit highly localized spaces known as microenvironments, which are defined by distinct physical and chemical characteristics. These include oxygen concentration, pH, temperature, light availability, and nutrient levels. The conditions within a microenvironment can differ markedly from those in the surrounding area and significantly influence microbial growth, metabolism, and community structure.Microenvironments often display sharp physicochemical gradients over small spatial...
01:29Methods for Controlling Microbial Growth
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
01:17Microbial Biosensors
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
01:19Key Techniques in Microbiology
Aseptic techniques prevent contamination, ensure experimental accuracy, and protect researchers and microbial cultures. These techniques are essential in clinical, industrial, and research settings where sterility is required.Maintaining Sterility in Laboratory PracticesScientists maintain sterility by sterilizing tools with heat or chemicals, disinfecting work surfaces, and handling cultures in controlled environments. Working near an open flame or within a laminar flow hood reduces the risk...