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Published on: February 8, 2019
Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager
Taylor Wintler1, Monica Zherebtsov2, Susanne Carmack3
1Washington State University, Elson S. Floyd College of Medicine, Spokane, WA, USA.
Abstract:
We present the case of an acute onset ANCA positive vasculitis in an asymptomatic COVID-19 infected teenager, resulting in significant colonic damage. The patient was initially diagnosed with Henoch-Schönlein purpura and presented with worsening symptoms with significant necrosis of her perineum and rectum requiring surgical debridement and diverting colostomy. As a part of her work-up, she tested positive for COVID-19 total IgG/IgM antibodies and ANCA antibodies. This case complements previously reported cases of COVID-19 induced autoimmune disease in children but is novel in describing extensive intestinal disease as a result of an autoimmune vasculitis in a child.
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