Accuracy comparison study of new smartphone-based semen analyzer versus laboratory sperm quality analyzer

Area of Science:

• Reproductive Medicine
• Medical Technology
• Urology

Background:

• Semen analysis (SA) is crucial for evaluating male infertility.
• Conventional laboratory-based SA methods can be time-consuming and inaccessible.
• There is a need for convenient and accurate self-assessment tools for seminal parameters.

Purpose of the Study:

• To evaluate the clinical efficacy of a portable smartphone-based App assisted semen analysis (SA) system, O'VIEW-M PRO®.
• To compare the accuracy of the O'VIEW-M PRO® system with traditional laboratory-based manual microscopic SA and computer-assisted semen analysis (CASA).
• To assess the system's utility for self-evaluation of seminal parameters.

Main Methods:

• A total of 39 semen samples were analyzed between January and May 2021.
• Sperm concentration and motility were measured using the O'VIEW-M PRO® smartphone app.
• Results were compared against manual microscopic SA (Makler Counting Chamber) and CASA.

Main Results:

• The O'VIEW-M PRO® system demonstrated high sensitivity (92.6%) and overall accuracy (84.6%) for classifying sperm concentration and motility.
• Coefficient factors between O'VIEW-M PRO® and laboratory methods ranged from 0.655 to 0.666 for sperm density and motility.
• The system showed good performance in classifying samples based on established sperm concentration and motility criteria.

Conclusions:

• The smartphone-based App assisted SA system, O'VIEW-M PRO®, is clinically effective and accurate.
• The system facilitates easy self-diagnosis of semen parameters at home.
• This technology can potentially improve treatment adherence and outcomes for infertile men.